Nordvest is a gangsterfilm set in the suburbs of Copenhagen. Casper (18), the oldest of 3 siblings, survives life on the streets by committing burglaries for the neighbourhood boss, Jamal. When Casper gets an offer to work for Jamal’s rival Björn, he jumps at the chance for a better life, making his way into a world of drugs and prostitution. As things escalate between Björn and Jamal, Casper finds himself and his family dead center of a conflict, that threatens to destroy them.

Anna, a young and aspiring actress who has not had much success, offers to care for the father of Jorgen, who has been burdened with the responsibility. The father, Walentin, is in a mostly comatose state, which makes him the perfect audience for Anna, who begins acting out her scenes in front of him. Gradually, Walentin shows signs of recovery -- but is this due to Anna's kindness, or is it possible that the old man is a pretty good actor himself?