In Rome, a Virgin Mary statue is found crying blood. Pondering on the implications of the existence of miracles, and eventually, the existence of God, the people involved in the enigma start losing their minds.

Three best friends make the most of their last summer weekend together before going their separate ways to college.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

An elite team of FBI profilers analyze the country's most twisted criminal minds, anticipating their next moves before they strike again. The Behavioral Analysis Unit's most experienced agent is David Rossi, a founding member of the BAU who returns to help the team solve new cases.