The story of New Jersey-based Italian-American mobster Tony Soprano and the difficulties he faces as he tries to balance the conflicting requirements of his home life and the criminal organization he heads. Those difficulties are often highlighted through his ongoing professional relationship with psychiatrist Jennifer Melfi. The show features Tony's family members and Mafia associates in prominent roles and story arcs, most notably his wife Carmela and his cousin and protégé Christopher Moltisanti.

12-year-old David is accidentally knocked out in the forest near his home, but when he awakens eight years have passed. His family is overjoyed to have him back, but is just as perplexed as he is that he hasn't aged. When a NASA scientist discovers a UFO nearby, David gets the chance to unravel the mystery and recover the life he lost.