Bob and Joe are two prisoners locked up in the Latin American maximum security prison of Santa Consuelo. The two manage to escape during an attack by the revolutionaries commanded by Napoleon Duarte and pretend to be friars, taking refuge in the mission of San Rolando. In the mission, in which monks and Indians live in harmony, the two escapees become Father Orso and Father Zaccaria and win the affection of all.

When their plane crashes, 25 schoolboys find themselves trapped on a tropical island, miles from civilization.