The New York office of the FBI brings to bear all their talents, intellect and technical expertise on major cases in order to keep their city and the country safe.

Returning from vacation, the Miller family find their home has been broken into. After cleaning up the mess they continue with their lives, shaking off the feeling of being violated. But little do they know the nightmare has just begun.

In cases ripped from the headlines, police investigate serious and often deadly crimes, weighing the evidence and questioning the suspects until someone is taken into custody. The district attorney's office then builds a case to convict the perpetrator by proving the person guilty beyond a reasonable doubt. Working together, these expert teams navigate all sides of the complex criminal justice system to make New York a safer place.