Roberto is a doctor in a small town near Naples. He suffers from a severe heart disease and he is heading toward an American hospital for a dangerous surgery with little or no hope of surviving. Therefore he talks to his best friend since childhood, Michele, a columnist at the local newspaper, explaining his last and long-wanted desire: having sex once with his Swedish beautiful wife, Frida.

A businessman from the United States returns to Italy for the first time in four decades only to discover that an old girlfriend of his, along with her brother, have involved him in a massive hoax.