Las Vegas showroom magician Cris Johnson has a secret which torments him: he can see a few minutes into the future. Sick of the examinations he underwent as a child and the interest of the government and medical establishment in his power, he lies low under an assumed name in Vegas, performing cheap tricks and living off small-time gambling "winnings." But when a terrorist group threatens to detonate a nuclear device in Los Angeles, government agent Callie Ferris must use all her wiles to capture Cris and convince him to help her stop the cataclysm.

Tim and Eric Awesome Show, Great Job! is an American sketch comedy television series, created by and starring Tim Heidecker and Eric Wareheim, which premiered February 11, 2007 on Cartoon Network's Adult Swim comedy block and ran until May 2010. The program features surrealistic and often satirical humor, public-access television–style musical acts, bizarre faux-commercials, and editing and special effects chosen to make the show appear camp. The program featured a wide range of actors, spanning from stars such as Will Ferrell, John C. Reilly, David Cross, Bob Odenkirk, Will Forte and Zach Galifianakis, to alternative comedians like Neil Hamburger, to television actors like Alan Thicke, celebrity look-alikes and impressionists. The creators of the show have described it as "the nightmare version of television."

When petty criminal Earl Hickey wins the lottery, he sets off on a quest to repair his questionable karma.