Mia, an aspiring actress, serves lattes to movie stars in between auditions and Sebastian, a jazz musician, scrapes by playing cocktail party gigs in dingy bars, but as success mounts they are faced with decisions that begin to fray the fragile fabric of their love affair, and the dreams they worked so hard to maintain in each other threaten to rip them apart.

Celeste and Jesse met in high school and got married young. They laugh at the same jokes and finish each other’s sentences. They are forever linked in their friends’ minds as the perfect couple – she, a high-powered businesswoman and budding novelist; he, a free spirit who keeps things from getting boring. Their only problem is that they have decided to get divorced. Can their perfect relationship withstand this minor setback?

Baby Daddy follows Ben, a young man in his early 20s living the life of a bachelor in New York City with his buddy, Tucker, and his brother, Danny. Their lives are turned upside down when they come home one day to find a baby girl left on the doorstep by an ex-girlfriend of Ben's. After much deliberation, Ben decides to raise the baby with the help of his friends and his protective and sometimes over-bearing mother, Bonnie, and his close female friend, Riley.

Jessica Day is an offbeat and adorable girl in her late 20s who, after a bad breakup, moves in with three single guys. Goofy, positive, vulnerable and honest to a fault, Jess has faith in people, even when she shouldn't. Although she's dorky and awkward, she's comfortable in her own skin. More prone to friendships with women, she's not used to hanging with the boys—especially at home.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

Once a rock star photographer, Stewart Fox's years of drug and alcohol abuse have relegated him to shooting erotic photos of model/actress wannabes out of his home to make ends meet. In a desperate attempt to get back into the spotlight, he hires a struggling art student to turn the camera on him for a self-published autobiography. But with so many sordid stories and complicated characters pressing buttons all around him, eventually something is bound to snap.

Newlywed Melinda Gordon tries to help the dead communicate with loved ones, but sometimes the messages she receives are intense and confusing. Most of Melinda's efforts involve resolving conflicts that are preventing the spirits from passing over.

Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.

Allison Dubois works in the District Attorney’s office using her natural intuition about people and her ability to communicate with the dead to help to solve crimes. Her dreams often give her clues to the whereabouts of missing people.

Gino Felino is an NYPD detective from Brooklyn who knows everyone and everything in his neighborhood. Killing his partner was someone's big mistake... because he's now out for justice.