A trio of beautiful girls set out to revolutionize life at a grungy American university: the dynamic leader Violet Wister, principled Rose and sexy Heather. They welcome transfer student Lily into their group which seeks to help severely depressed students with a program of good hygiene and musical dance numbers.

Liz Lemon, the head writer for a late-night TV variety show in New York, tries to juggle all the egos around her while chasing her own dream.