A group of heroic firefighters at Seattle Fire Station 19—from captain to newest recruit—risk their lives and hearts both in the line of duty and off the clock. These brave men and women are like family, literally and figuratively, and together they put their own lives in jeopardy as first responders to save the lives of others.

After his wife kicks him out, an anxious comedian is lured in by an intriguing woman with a stalker.

In the gritty world of the NYPD, no one's tougher than Detective Robert Ironside. He and his trusted, handpicked team of specialists will do whatever it takes to solve New York's most difficult and notorious crimes - even if it means breaking the rules. As a detective, his instincts are second to none, and those around him have to stay on their toes if they want to keep up...because when his spine was shattered by a bullet two years ago, Ironside swore he'd never let a damn wheelchair slow him down.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.

Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.

After 20 years in prison, a wrongfully convicted man is released from prison for rape and murder. He reconnects with his adult daughter and tries to rebuild his life. The victim's husband has become a recluse, obsessed with a true crime documentary about the case, and tries to contact law enforcement to reopen the investigation and find the real killer, but they consider it case closed. Then the prosecutor is kidnapped in a desperate attempt to convince her to find the real killer.