New York's toughest lady detectives re-team to solve the murder of a homeless transient who had been terrorizing the residents of a posh apartment building with screaming threats, insults and physical intimidation. Though the cops think the culprit is another street person, Cagney and Lacey believe the real killer is one of the tenants, many of whom have ample reason to have murdered the boorish bum.

The story of the discovery of the AIDS epidemic and the political infighting of the scientific community hampering the early fight with it.

Theorizing that one could time travel within his own lifetime, Dr. Sam Beckett stepped into the Quantum Leap accelerator and vanished... He woke to find himself trapped in the past, facing mirror images that were not his own and driven by an unknown force to change history for the better. His only guide on this journey is Al, an observer from his own time, who appears in the form of a hologram that only Sam can see and hear. And so Dr. Beckett finds himself leaping from life to life, striving to put right what once went wrong and hoping each time that his next leap will be the leap home.