He is six years old and his schoolmates call him Dirty Face. That is why he washes his face over and over again, but it is useless.

Miguel, a young psychiatrist working in Madrid, learns that his wife has just dumped him for no one else than his own father while he's expecting his mother-in-law's visit, who's come to the city on a medical revision, and doesn't know anything about her daughter's affair; to make things worse, one of Miguel's deranged patients has just stolen his wallet. Going to his patient's home to retrieve his wallet he'll meet instead his spontaneous and outspoken hairdresser sister Jasmina, who's bound to change Miguel's ordered, upper-middle-class world for good.

Although on vacation, the Spaniards returned to the Americas convinced that there, in addition to the language, the spirit of El Dorado was still preserved. However, the old dangers still lurked.