Attacked by a werewolf in Newcastle, Tom returns to Birmingham where he meets up with his pal Jay (James D Messer) who has a new girlfriend named Kate (Toni Bird). Tom owes money to local wannabe gangster Dino (Dean Greatbatch) but has bigger problems in his regular lycanthropic attacks, which leave a trail of zero-budget death and destruction across the West Midlands.

After the mobster who murdered his partner is acquitted, semicorrupt detective Robert Bryant hires a beautiful female assassin, Maria, to kill him. When he discovers that he cannot afford Maria's services, Bryant is forced to hire another assassin, Madison, to kill her. Maria survives the doublecross and sets out to collect what's owed to her, one way or another.