Hope, a down-to-earth, happily married mother of three has her tidy world turned upside down when her celebrity sister moves in. Faith was living the Hollywood life as a soap opera star before her character was killed off.

Over one night in New York City, lives of disparate strangers intersect by fate and circumstance.

In 24 hours, 5 worlds collide in the forgotten neighborhoods of New York City.

Welcome to the front lines of AIDS activism, where the latest enemy raids are being run by a band of unlikely warriors: two drag queens, an HIV-positive man with tiny gemstones dotting his bald head, and his HIV-positive sister.

Manny tries to get his crack addict brother, Danny, to clean up.