Already taking a gamble settling in the uncharted west, the peaceful settlers of a town destined for railroad greatness suddenly find themselves being ruthlessly gunned down. With no law and order to be found, justice falls onto the shoulders of an elderly rancher and an accomplished, but retired, gunslinger.

A self-loathing, alcoholic writer attempts to repair his damaged relationships with his daughter and her mother while combating sex addiction, a budding drug problem, and the seeming inability to avoid making bad decisions.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.