An irreverent look at parenthood through the point of view of an acerbic working mother, along with her stay-at-home husband and opinionated parents.

Dexter Morgan, a blood spatter pattern analyst for the Miami Metro Police also leads a secret life as a serial killer, hunting down criminals who have slipped through the cracks of justice.

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

Set in the 1800's, the town of Flat ridge is over run by a band of outlaws looking for lost treasure said to be buried somewhere in town. In their quest for dominance, the outlaws kill Sally, a whore who happens to be the sister of Rachel and a 1/5 member of the Roses Gang. With the weight of grief on her heart, Rachel decides to shed her new found religious faith to bring vengeance upon her sister's killers. After placing Sally to rest, she goes in search of her former posse to assist her in the reckoning of the outlaws wrong doing.

In the unreal world of Sacred Heart Hospital, John "J.D." Dorian learns the ways of medicine, friendship and life.

Dray is a young playboy whose only objective in life seems to be to have sex with as many girls as he can without getting caught by his girlfriend Lisa. Dray's sister Jenny and her friend Katrina plan to show him that the way he lives is wrong and organize a party in Malibu, inviting all of his girlfriends.