Embezzler, shill, all around confidence man S. Quentin Quale is heading west to find his fortune; he meets the crafty but simple brothers Joseph and Rusty Panello in a train station, where they steal all his money. They're heading west, too, because they've heard you can just pick the gold off the ground. Once there, they befriend an old miner named Dan Wilson whose property, Dead Man's Gulch, has no gold. They loan him their last ten dollars so he can go start life anew, and for collateral, he gives them the deed to the Gulch. Unbeknownst to Wilson, the son of his longtime rival, Terry Turner (who's also in love with his daughter, Eva), has contacted the railroad to arrange for them to build through the land, making the old man rich and hopefully resolving the feud. But the evil Red Baxter, owner of a saloon, tricks the boys out of the deed, and it's up to them - as well as Quale, who naturally finds his way out west anyway - to save the day.

Two buddies who rise from fly-by-night wildcatters to oil tycoons over a twenty year period both love the same woman. McMasters and Sand come to oil towns to get rich. Betsy comes West intending to marry Sand but marries McMasters instead. Getting rich and losing it all teaches McMasters and Sand the value of personal ties.

Maisie becomes attached to a dirt-poor farmer and his family as they try to make ends meet joining hundreds of others digging for gold in a previously panned-out ghost town.

An out-of-work professor gets a break from an old college buddy to teach at an exclusive girl's school. But events conspire against him: he finds an abandoned child which he takes under his wing, despite the school's rules against teachers having a family; and the girls in the school resent his replacing a handsome and popular teacher, and do everything in their power to get him fired.