Set in 1932 Los Angeles, the series focuses on the origin story of famed defense lawyer Perry Mason. Living check-to-check as a low-rent private investigator, Mason is haunted by his wartime experiences in France and suffering the effects of a broken marriage. L.A. is booming while the rest of the country recovers from the Great Depression — but a kidnapping gone very wrong leads to Mason exposing a fractured city as he uncovers the truth of the crime.

A young Venezuelan freedom fighter seeks asylum in the United States, but his heart remains in the fight back home.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

Sam hasn't been back to his homeland of Puerto Rico in more than 60 years, but when he returns after winning an all-expense-paid vacation, he gets kidnapped by a group of Latin revolutionaries, who welcome him to the first cultural boot camp.

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.