The life of internationally renowned artist and activist Nan Goldin is told through her slideshows, intimate interviews, ground-breaking photography, and rare footage of her personal fight to hold the Sackler family accountable for the overdose crisis.

A Baltimore teenager who picks up a second-hand camera starts snapping his way to stardom, soon turning into a nationwide sensation, with a fateful choice between his life and his art.

Nan Goldin's slide show “The Ballad of Sexual Dependency” converted, mixed and screened as a film by the artist, portraying the American underground culture, the no wave scene, post-Stonewall gay subculture, among others.

Blessed with a keen sense of smell and cursed with a philandering pornographer husband, a parasitic mother, and a pair of delinquent children, the long-suffering Francine Fishpaw turns to the bottle as her life falls apart -- until deliverance appears in the form of a hunk named Todd Tomorrow.