Never Mind the Buzzcocks is a comedy panel game show with a pop and rock music theme. The show is infamous for its dry, sarcastic humour and scathing, provocative attacks on the pop industry.

The U.S. government, eager to protect the nation's avacado supplies, recruits feminist professor Margo Hunt to make contact with the Piranha Women, an all-female tribe who believe men are only good as a source of food. Accompanying Dr. Hunt on her trip are Jim, a guide of questionable competence, and Bunny, a student of unquestionable incompetence.