In 1973, 15-year-old William Miller's unabashed love of music and aspiration to become a rock journalist lands him an assignment from Rolling Stone magazine to interview and tour with the up-and-coming band, Stillwater.

The Herlihys are a working class family from Chicago whose three children take wildly divergent paths: Brian joins the Marines right out of High School and goes to Vietnam, Michael becomes involved in the civil rights movement and after campaigning for Bobby Kennedy and Eugene McCarthy becomes involved in radical politics, and Katie gets pregnant, moves to San Francisco and joins a hippie commune. Meanwhile, the Taylors are an African-American family living in the deep South. When Willie Taylor, a minister and civil rights organizer, is shot to death, his son Emmet moves to the city and eventually joins the Black Panthers, serving as a bodyguard for Fred Hampton.

Several Black men take a cross-country bus trip to attend the Million Man March in Washington, DC in 1995. On the bus are an eclectic set of characters including a laid-off aircraft worker, a man whose at-risk son is handcuffed to him, a black Republican, a former gangsta, a Hollywood actor, a cop who is of mixed racial background, and a white bus driver. All make the trek discussing issues surrounding the march, including manhood, religion, politics, and race.