Matt and George investigate a series of strange occurrences involving newcomers, who are found to be programmed to carry out someone's dirty work. The method by which they are brainwashed dates back to the slave ship's rebellion group, the Udara, who, we discover, Susan was a part of. Susan and George's lives are further disrupted when Buck enrols in the police academy.

When detectives Sikes and Francisco are presented with the mysterious death of an Eeno, Matt is stupefied to discover that George rudely snubs the case. He, like most newcomers, reviles the outcast Eenos. As the case unfolds, George has to reassess his prejudices, and George's family help save the city from an alien threat originating in an Eeno waste disposal facility.

Annie marries Jack Westford, a cop when they met. Six years later, Jack is now working as a security guard in a bank and feels that he was unfairly fired from the force. He also appears to be no longer interested in Annie and has an affair with another bank employee. Among his duties is delivering old money for disposal. He comes up with a plan to steal the money and run away. Part of his plan is to fake his death and frame Annie. While the police suspect that she killed Jack and knows where the money is, there's also an insurance investigator on her back.

Dr. Mark Sloan is a good-natured, offbeat physician who is called upon to solve murders.

Follow the lives of a group of young adults living in a brownstone apartment complex on Melrose Place, in Los Angeles, California.

Together, a weary cop and an all business FBI agent, team up to catch the latest homicidal manic: The Rain Killer. Just when they think that all the clues have been washed away, they find the one last clue; the one that's been in plain sight.

After Leila, his boss's daughter, is kidnapped by psychopathic plague victim Decker, chauffeur Chazz teams up with plague-infected mercenary Luger to penetrate the toxic & off-limits Plague Zone and bring her back alive.

Columbo is a friendly, verbose, disheveled-looking police detective who is consistently underestimated by his suspects. Despite his unprepossessing appearance and apparent absentmindedness, he shrewdly solves all of his cases and secures all evidence needed for indictment. His formidable eye for detail and meticulously dedicated approach often become clear to the killer only late in the storyline.