After getting bitten by a rabid dog, Clara must stay locked in the small cabin where she lives with her mother and husband for 40 days. While the town is assaulted by a pack of savage dogs, Clara's seclusion causes a growing desire for freedom. To escape, she will have to overcome her family's fear and determination to protect her.

A group of women, including Skipper, the wealthy young Jennifer and the domineering Nan, journey from the United States to South America in hopes of easily adopting children. Unfortunately, their plans are complicated by local laws that require the women to live in the foreign nation for an extended period before they can take in orphaned kids. While stuck in another country, the women bond as they share their aspirations and anxieties.

A telenovela that dramatizes the romances and rivalries between two brothers and two sisters in Mexico between the years 1885 and 1900.