Opposite Lives tells the story of Miguel (Leo Rosa), a young rich man of a traditional family, and Joana (Maytê Piragibe), a student and tourist guide who lives in a slum. Although dating an elegant and rich fashion designer, Erínia (Lavínia Vlasak), Miguel and Joana fall in love for each other and they decide to get married.

Maria is an orphan girl who suffers from her stepmother's wickedness. She then decides to escape in search of the fringes of the sea and takes a long walk through Brazilian folk tales. On his journey, he meets several fantastic characters.