In France, terrorist groups and intelligence agencies battle in a merciless war everyday, in the name of radically opposed ideologies. Yet, terrorist and secret agents lead almost the same lives. Condemned to secrecy, these masters of manipulation follow the same methods. Alex and Al Barad are two of them. The former is the head of the D.G.S.E.'s (Direction Générale de la Sécurité Extérieure, the French equivalent of the CIA or the MI6) counter-terrorism unit while the latter reigns over a terrorist network, and both fight using the most ruthless of weapons: human beings.

Raised as a slave, Danny is used to fighting for his survival. In fact, his "master," Bart, thinks of him as a pet and goes as far as leashing him with a collar so they can make money in fight clubs, where Danny is the main contender. When Bart's crew is in a car accident, Danny escapes and meets a blind, kindhearted piano tuner who takes him in and uses music to free the fighter's long-buried heart.

Wounded to the brink of death and suffering from amnesia, Jason Bourne is rescued at sea by a fisherman. With nothing to go on but a Swiss bank account number, he starts to reconstruct his life, but finds that many people he encounters want him dead. However, Bourne realizes that he has the combat and mental skills of a world-class spy—but who does he work for?

Immortal Xavier St. Cloud has mortals shoot his Immortal opponents so he can take their heads. Joe tells Duncan about the killings to warn him, and soon St. Cloud and his henchmen show up at the dojo. Duncan discovers the supposedly-dead Horton is working with St. Cloud, and Joe knew that Horton was alive. Meanwhile, an army intelligence officer named Renee Delaney gets involved while she is investigating one of the men working with St. Cloud.

Duncan MacLeod cannot die -- he is a 400-year-old immortal, who has seen his share of humanity's history. Still, he risks his life in battle against other immortals and tries to save people from harm.