A man tries to save his son from making a devastating choice.

In 19th century Baltimore, Isabel Porter, a girl stricken with grief from her parents' untimely death, voluntarily checks herself into the Rosewood Institute. Subjected to bizarre and increasingly violent pseudo-scientific experiments in personality modification, brainwashing and mind control, she must escape the clutches of the Rosewood and exact her revenge, or else be forever lost.

Two lost souls meet at a subway station and form an unexpected connection on the night they have both decided to commit suicide.