Taking place on the last day of the Creeper’s twenty-three-day feeding frenzy, as the skeptical Sergeant Tubbs teams up with a task force hellbent on destroying the Creeper for good. The Creeper fights back in gory glory as its enemies grow closer than ever before to learning the secret of its dark origins.

In Dallas, witnesses against a drug-lord are murdered in a safe-house.The testimony of FBI agents becomes the only chance to keep him in prison. They are lodged in another safe-house, but the place is invaded and the agents are executed. However, Kate is only wounded, and her boyfriend Nick believes there is a traitor in the agency and takes her to his ranch to protect her life.