A group of friends get lost in the seedy streets where they encounter a crazed gang of homeless derelicts that seizes them and kills them one by one. The surviving man escapes on foot, naked and unarmed, with a pack of depraved transients in pursuit, and only seconds away from capture.

When Emily, a librarian-to-be, is assigned to tutor Mateo, a struggling undergrad, in American Lit, they do not get along; but when the discussion turns from classics to confessions, they learn something that could change their lives forever.