An anthology film and friendship tale that takes place in St. Louis in the late 1980s during the height of the AIDS crisis. The story follows a man who has just found out one of his friends is HIV positive — a death sentence that, back then, usually meant the person had about twelve months to live. The main character goes on a game show in order to raise money for a car to drive his friend to Mexico where he can receive a popular, but later proven ineffective, treatment for the virus.

The streets of Los Angeles are being littered with murdered sex workers, as a sinister killer tempts desperate women into dangerous traps.

Models all over town are ending up on the wrong side of a razor-sharp blade, and police are baffled by the surgical precision of the corpse mutilation. David, a local photographer who knew a couple of the murdered women, finds his world turn upside down as the streets run red with blood.