The trials and tribulations of finding love and companionship — the second time around. Newly divorced Alex, who is missing his kids and trying to keep himself together. Alex's co-worker Helen thinks she has it together, but she drinks too much in order to cope with her fiance's untimely death. It's no surprise then when these two overworked public relations executives share an ill-fated night of passion and are forced to cope with the awkward aftermath.

Gavin Larson's band, The Zebras, is on top, living every rock and roll fantasy until Gavin's band mates perish in a fiery plane crash. Tormented by the memory of his band and the fading of his once bright star, Gavin begins a downward spiral of denial, delusion, and self-medication. His only chance at redemption rests in the people he's screwed and the bridges he's burned. Gavin's plan? To form a new band and rule the world.

Best friends, Carl and Lester, find themselves magically transported into an alternate universe straight out of a real-life adult movie. Hilarity ensues as they embark upon a journey of adult-themed mayhem while Carl ultimately finds true love in the most unlikely of places.

Mick St. John is a captivating, charming and immortal private investigator from Los Angeles, who defies the traditional blood-sucking norms of his vampire tendencies by using his wit and powerful supernatural abilities to help the living.

Tim and Eric Awesome Show, Great Job! is an American sketch comedy television series, created by and starring Tim Heidecker and Eric Wareheim, which premiered February 11, 2007 on Cartoon Network's Adult Swim comedy block and ran until May 2010. The program features surrealistic and often satirical humor, public-access television–style musical acts, bizarre faux-commercials, and editing and special effects chosen to make the show appear camp. The program featured a wide range of actors, spanning from stars such as Will Ferrell, John C. Reilly, David Cross, Bob Odenkirk, Will Forte and Zach Galifianakis, to alternative comedians like Neil Hamburger, to television actors like Alan Thicke, celebrity look-alikes and impressionists. The creators of the show have described it as "the nightmare version of television."

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.