Three people from different walks of life find themselves trapped inside a stalled elevator. What at first seems like an inconvenience rapidly escalates into a nightmare.

Claire Bannion, a widowed mother of two young daughters, has the gift of extrasensory perception that torments her after she "sees" her husband die in a fishing accident but is powerless to prevent it. Two years later when Claire's neighbors are murdered, she reluctantly agrees to use her clairvoyance to help with the police investigation.

Sarah Nolan is a newly divorced woman cautiously rediscovering romance with the enthusiastic but often misguided help of her well-meaning family. As she braves a series of hilarious disastrous mismatches and first dates, Sarah begins to trust her own instincts again and learns that, no matter what, it's never a good idea to give up on love.

Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.