Great white sharks bio-engineered to be the size of piranhas with the purpose of living in rich peoples exotic aquariums, terrorize New York City when they get into the water supply and do what great white sharks do best.

Four kids named Dylan, Sam, Ash, and Iko form a club called Team Toon, drawn together by their shared love of cartooning. In their club they produce the popular online viral series called "Psycho Squirrel", and they are popular at their school for their creation. However, their club isn't just a hobby. Dylan discovers that they have the power to make their cartoon creations come to life and use it to form a superhero squad of the same name to fight rogue cartoon monsters that take over the minds of innocent humans.