Archetypal buddy cops Riggs and Murtaugh are back for another round of high-stakes action, this time setting their collective sights on bringing down a former Los Angeles police lieutenant turned black market weapons dealer. Lorna Cole joins as the beautiful yet hardnosed internal affairs sergeant who catches Riggs's eye.

Seward Sanitarium has been plagued by strange events, all following the takeover of a nearby abbey by Transylvanian Count Dracula. Visiting professor, Van Helsing, believes it to be the work of vampires, and when patients and staff begin turning up dead, realizes that he must act quickly to save the others.