Beautiful vampire Djuna tries to resist the advances of the handsome, human screenwriter Paolo, but eventually gives in to their passion. When her seductive and highly volatile sister Mimi unexpectedly comes to visit, she threatens Djuna's new relationship, and the whole vampire community becomes endangered.

A chronological look at films by, for, or about gays and lesbians in the United States, from 1947 to 2005, Kenneth Anger's "Fireworks" to "Brokeback Mountain". Talking heads, anchored by critic and scholar B. Ruby Rich, are interspersed with an advancing timeline and with clips from two dozen films. The narrative groups the pictures around various firsts, movements, and triumphs: experimental films, indie films, sex on screen, outlaw culture and bad guys, lesbian lovers, films about AIDS and dying, emergence of romantic comedy, transgender films, films about diversity and various cultures, documentaries and then mainstream Hollywood drama. What might come next?

The life and times of Baltimore film maker and midnight movie pioneer, John Waters.