When a strange signal pulsates through all cell phone networks worldwide, it starts a murderous epidemic of epic proportions when users become bloodthirsty creatures, and a group of people in New England are among the survivors to deal with the ensuing chaos after.

John "Breacher" Wharton leads an elite DEA task force that takes on the world's deadliest drug cartels. When the team successfully executes a high-stakes raid on a cartel safe house, they think their work is done – until, one-by-one, the team members mysteriously start to be eliminated. As the body count rises, everyone is a suspect.