Dave and Joe, just evicted from their Oakland apartment, turn to stealing cars and dealing Fluoride to make their financial ends meet. One night they find Summer Hayes, star of a popular 1990's teen soap, in the trunk of a stolen automobile. Shoot-outs, car chases, and overdoses ensue. In the Fluoride heightened world of "Medias Res", nothing is what it at first appears to be.

Minnie Goetze is a 15-year-old aspiring comic-book artist, coming of age in the haze of the 1970s in San Francisco. Insatiably curious about the world around her, Minnie is a pretty typical teenage girl. Oh, except that she’s sleeping with her mother’s boyfriend.