When Jack and Sally announce that they're splitting up, this comes as a shock to their best friends Gabe and Judy. Maybe mostly because they also are drifting apart and are now being made aware of it. So while Jack and Sally try to go on and meet new people, the marriage of Gabe and Judy gets more and more strained, and they begin to find themselves being attracted to other people.

A hapless talent manager named Danny Rose, by helping a client, gets dragged into a love triangle involving the mob. His story is told in flashback, an anecdote shared amongst a group of comedians over lunch at New York's Carnegie Deli. Rose's one-man talent agency represents countless incompetent entertainers, including a one-legged tap dancer, and one slightly talented one: washed-up lounge singer Lou Canova, whose career is on the rebound.

Bill, an intellectually disabled man, ventures out into the world for the first time, having spent most of his life in a dreary inner city institution. He is taken in by a kind family and learns what it means to love and be loved for the first time in his life.

New York City detective Daniel Ciello agrees to help the United States Department of Justice help eliminate corruption in the police department, as long as he will not have to turn in any close friends. In doing so, Ciello uncovers a conspiracy within the force to smuggle drugs to street informants.

A New York-based bounty hunter who makes a living chasing and capturing bail jumpers matches wits with a heavily-armed drug dealer in this pilot to a prospective series.

A sex education teacher falls for a construction worker with a gambling problem.

A young woman, Joy, refuses to have sex with her boyfriend. But after being raped, she becomes obsessed with sex and starts having intercourse indiscriminately.