Dr. Mary Harris, a single mother and emergency doctor by day, also moonlights as an underground angel of death - helping terminally ill patients who want to die and slip away on their own terms. So far Mary has managed to stay under the radar; but business is booming, and her double life is getting complicated. When her world starts to unravel, Mary realizes she's going to have to fight dirty if she's going to stay in the killing game.

Follow a group of high school freshmen, sophomores, juniors, and seniors from Degrassi Community School, a fictional school in Toronto, Ontario, as they encounter some of the typical issues and challenges common to a teenager's life.