Needle paints a harrowing picture of a Liverpool overrun by drugs, charting a young man's nightmarish descent into intravenous heroin use and AIDS and a police and political leadership incapable of the imagination or courage necessary to respond to the drug problem.

Linda's out on her hen night, her fiance is out on his stag night. Linda is having major doubts about getting married, when both groups arrive at a club, to find the band fronted by her ex-boyfriend—and the love of her life—Peter. Linda has to decide: Does she stay and settle down, like her friends want her to, or does she chuck it all in and run away with Peter?