In 2007, the Writers Guild of America, the Screenwriters Union, hit an impasse in their contract negotiations with the Studios. At the center of the dispute was jurisdiction over the internet. Unable to make progress, the WGA called a strike which brought Hollywood to a halt for 100 days.

Deloris Van Cartier is again asked to don the nun's habit to help a run-down Catholic school, presided over by Mother Superior. And if trying to reach out to a class full of uninterested students wasn't bad enough, the sisters discover that the school is due to be closed by the unscrupulous chief of a local authority.