Explore the high-pressure experiences of police officers, paramedics and firefighters who are thrust into the most frightening, shocking and heart-stopping situations. These emergency responders must try to balance saving those who are at their most vulnerable with solving the problems in their own lives.

Perhaps their strikingly different personalities make the relationship between detective Jane Rizzoli and medical examiner Maura Isles so effective. Jane, the only female cop in Boston's homicide division, is tough, relentless and rarely lets her guard down, while the impeccably dressed Maura displays a sometimes icy temperament — she is, after all, more comfortable among the dead than the living. Together, the best friends have forged a quirky and supportive relationship; they drop the protective shield in each other's company, and combine their expertise to solve Boston's most complex cases.

Wiley Roth finds a severed human finger in his kitchen one night. Understandably freaked out, in a search across Los Angeles that brings them in contact with psychics, ineffectual police, crooked taxidermists, mysterious neighbors who might be on drugs, and a nine-fingered woman named Cheryl who might, improbably, end up being the girl of his dreams.

A Las Vegas team of forensic investigators are trained to solve criminal cases by scouring the crime scene, collecting irrefutable evidence and finding the missing pieces that solve the mystery.

Attempting to save his sick child, a memory repairman and former hitman, Jack Whitlock, is drawn back to a life he thought he had left behind. When he is blindsided, unintended consequences arise and cause everyone from law enforcement, his former boss and current job to begin to question his motives and close in on him for the truth.