John Mulaney and his kid pals tackle existential topics for all ages with catchy songs, comedy sketches and special guests in a nostalgic variety special.

A former professional dancer, Brooke, and her brother Cary, an aspiring actor, try to find their place in the world while wrestling with their feelings about their 13-year-old brother Chase's sudden rise to internet fame.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

An ex-cop turned con threatens to jump to his death from a Manhattan hotel rooftop. The NYPD dispatch a female police psychologist to talk him down. However, unbeknownst to the police on the scene, the suicide attempt is a cover for the biggest diamond heist ever pulled.

A struggling Asian American Theater company decides to put on a production of Gilbert & Sullivan's The Mikado.

When journalist Dennis gets assigned to write about Pretty Woman for Marquee magazine's “Hooray for Hollywood Hookers” issue, he invites five friends over to screen, celebrate and skewer the modern-day Cinderella story. The partiers include his roommate Tony, a burnt-out cruise ship crooner who's desperately looking for a new gig on land; Lauren, a relationship-challenged aspiring stand-up comic; Marcos, a sweet-natured attorney who never met a tangent he couldn't go off on; Ross, an Opera-loving video clerk with multiple tattoos and arsenal of movie fun facts at the ready; and Dr. Beverly Beaverman, the shrink next door who finds Freudian psychological meanings in everything she sees. Together, they do their best to make sense of the 1990 Richard Gere-Julia Roberts romantic comedy classic while discovering that the movie's themes—sex, money, sex for money—resonate in their lives in ways both ridiculous and profound.

In the criminal justice system, sexually-based offenses are considered especially heinous. In New York City, the dedicated detectives who investigate these vicious felonies are members of an elite squad known as the Special Victims Unit. These are their stories.