Mike and Dave are young, adventurous, fun-loving brothers who tend to get out of control at family gatherings. When their sister Jeanie reveals her Hawaiian wedding plans, the rest of the Stangles insist that the brothers bring respectable dates. After placing an ad on Craigslist, the siblings decide to pick Tatiana and Alice, two charming and seemingly normal women. Once they arrive on the island, however, Mike and Dave realize that their companions are ready to get wild and party.

In a futuristic world where the polar ice caps have melted and made Earth a liquid planet, a beautiful barmaid rescues a mutant seafarer from a floating island prison. They escape, along with her young charge, Enola, and sail off aboard his ship. But the trio soon becomes the target of a menacing pirate who covets the map to 'Dryland'—which is tattooed on Enola's back.