Bonnie and cousin Sylvia, two very young children, are left at home in Willoughby Hall while their parents travel overseas. Only the servants and the prowling wolves are their companions. News arrives that Lord and Lady Willoughby are missing and an evil looking governess suddenly arrives at the hall...

Matthew is a boy who just left school. He is handsome and athletic and believes himself to be gay. He retains a friendship with only one school friend, Phil, who has stuck by Matthew despite hostile reactions from his peers. As their relationship grows more intense, Phil's girlfriend Sharon and his classmates become vindictive and aggressive. The two friends find themselves ostracized by both friends and family and decide to run away.

Seymour Krelborn is a nerdy orphan working at Mushnik's, a flower shop in urban Skid Row. He harbors a crush on fellow co-worker Audrey Fulquard, and is berated by Mr. Mushnik daily. One day Seymour finds a very mysterious unidentified plant which he calls Audrey II. The plant seems to have a craving for blood and soon begins to sing for his supper.