In 19th century Baltimore, Isabel Porter, a girl stricken with grief from her parents' untimely death, voluntarily checks herself into the Rosewood Institute. Subjected to bizarre and increasingly violent pseudo-scientific experiments in personality modification, brainwashing and mind control, she must escape the clutches of the Rosewood and exact her revenge, or else be forever lost.

A peaceful alien planet faces annihilation, as the homeless remainder of the human race sets its eyes on Terra. Mala, a rebellious Terrian teenager, will do everything she can to stop it.