Branded a killer and hunted by the police, a half Native American newlywed must return to the ways of his fore-fathers to discover the truth behind the disappearance of his bride

Bizarre things start happening in the little New Mexico town where UFOs were spotted in 1947. Cut to 1999, when a cute high-school student saves the life of a teenage waitress. Surrounded by cliques of clever, angst-filled classmates, the two form a bond that threatens the survival of a secret universe involving superhuman powers, a yen for hot sauce and an alien gene pool.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.