A 10-year-old boy shares an intense bond with his mentally ill mother. The youth's life is turned upside down when his mother lapses into violent psychosis. A former psychiatrist takes pity on, and then custody of, the child.

Ray Barone is a successful sportswriter living on Long Island with his wife Debra, daughter Ally, and twin sons, Geoffrey and Michael. That's the good news. The bad news? Ray's meddling parents, Frank and Marie, live directly across the street and embrace the motto "Su casa es mi casa," infiltrating their son's home to an extent unparalleled in television history.