Some punks go into a small town and start hassling the gas station owner; Billy Ray Dalton a friend of the owner pulls a shot gun on them and tells them to go away. Later they go back and force the owner to tell them where Dalton lives. Now, Dalton a part time musician's out on a gig, when they go to his house and kill his pregnant wife, and take his daughter. Dalton follows them to try and get his daughter back.

Madame Lu has created three "Death Machines," a trio of martial arts experts who have been injected with a special serum, turning them into mindless zombies, capable only of murder, at Lu's command. Tasked with eliminating her enemies, the Death Machines go on a blood-soaked rampage, killing anyone in their path. After they massacre an entire dojo, leaving only one survivor, the Death Machines and Madame Lu herself become the targets of his vengeance...