Travis's tight social group of friends and lovers splits apart when his childhood friend, O'Brien becomes severely mentally ill. Now alone, the characters go their separate ways: Travis helps crowd-fund a socialist revolution in Mexico, O'Brien succumbs to mania and becomes a satirical Youtube celebrity, Kate seeks stability in online dating, and Lox embarks on his first indie rock tour. Their lives continue to cross paths and reconnect through the internet.

Adam, an amateur comedy video blogger, struggles to measure up to his best friend Brian, an egotistical musician. When they move in together for a summer, Brian's obsessive and manipulative behavior surrounding the release of his new album awakens the sociopath in both young men.