Éric and Patrice have been friends since high school. Over the years, they have both taken very different paths: Éric has become a hedonist, has a string of girlfriends and is always on the look out for a new one; Patrice has become a monogamous father with a very ordered life. After a drunken evening, the two childhood friends find themselves cast back into 1986, when they were 17 years old. This return to the past is a dream opportunity to try to change the path their lives will take. What will they do with this second chance?

Samba migrated to France 10 years ago from Senegal, and has since been plugging away at various lowly jobs. Alice is a senior executive who has recently undergone a burnout. Both struggle to get out of their dead-end lives. Samba's willing to do whatever it takes to get working papers, while Alice tries to get her life back on track until fate draws them together.

Josephine doesn't like her job and keeps on having relationships without a future. Her sister and parents keep pushing her to find a good husband. To shut them up, she creates a handsome Brazilian millionaire but her little white lie has a flip side - she loses everything to find the love of her life.

The story takes place in Carhaix, in the heart of Brittany. A small hospital, with a calm maternity clinic, where few births take place. Mathilde, a mid-wife, Firmine, a pediatric nurse, and Louise, the owner of the Carhaix bowling alley, are all friends and lead a happy existence. Catherine, director of the establishment's Human Resources, is sent to restructure the hospital and, most importantly, to eventually shut down the maternity clinic, which is losing money. Four women whose age, personalities, and origins are different, but who will form a quartet overflowing with humanity and humor as they join forces to save the clinic. Life, love, friendship, Brittany and... bowling.